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Verification of the Efficacy of Mexiletine Treatment for the A1656D Mutation on Downgrading Reentrant Tachycardia Using a 3D Cardiac Electrophysiological Model
The SCN5A mutations have been long associated with long QT variant 3 (LQT3). Recent experimental and computation studies have reported that mexiletine effectively treats LQT3 patients associated with the A1656D mutation. However, they have primarily focused on cellular level evaluations and have onl...
Autores principales: | Qauli, Ali Ikhsanul, Yoo, Yedam, Marcellinus, Aroli, Lim, Ki Moo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598628/ https://www.ncbi.nlm.nih.gov/pubmed/36290499 http://dx.doi.org/10.3390/bioengineering9100531 |
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