Cargando…

Imaging Effector Memory T-Cells Predicts Response to PD1-Chemotherapy Combinations in Colon Cancer

Often, patients fail to respond to immune checkpoint inhibitor (ICI) treatment despite favourable biomarker status. Numerous chemotherapeutic agents have been shown to promote tumour immunogenicity when used in conjunction with ICIs; however, little is known about whether such combination therapies...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goggi, Julian L., Khanapur, Shivashankar, Hartimath, Siddesh V., Ramasamy, Boominathan, Cheng, Peter, Chin, Hui-Xian, Tang, Jun-Rong, Hwang, You-Yi, Robins, Edward G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598730/ https://www.ncbi.nlm.nih.gov/pubmed/36289605 http://dx.doi.org/10.3390/biomedicines10102343

Ejemplares similares

Imaging Memory T-Cells Stratifies Response to Adjuvant Metformin Combined with αPD-1 Therapy
por: Goggi, Julian L., et al.
Publicado: (2022)

Granzyme B PET Imaging in Response to In Situ Vaccine Therapy Combined with αPD1 in a Murine Colon Cancer Model
por: Hartimath, Siddesh V., et al.
Publicado: (2022)

An Improved Synthesis of N-(4-[(18)F]Fluorobenzoyl)-Interleukin-2 for the Preclinical PET Imaging of Tumour-Infiltrating T-cells in CT26 and MC38 Colon Cancer Models
por: Khanapur, Shivashankar, et al.
Publicado: (2021)

Imaging Adipose Tissue Browning using Mitochondrial Complex-I Tracer [(18)F]BCPP-EF
por: Goggi, Julian L., et al.
Publicado: (2022)

Granzyme B PET Imaging of Combined Chemotherapy and Immune Checkpoint Inhibitor Therapy in Colon Cancer
por: Goggi, Julian L, et al.
Publicado: (2021)

Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy Response
por: Goggi, Julian L., et al.
Publicado: (2022)

Granzyme B PET Imaging Stratifies Immune Checkpoint Inhibitor Response in Hepatocellular Carcinoma
por: Goggi, Julian L., et al.
Publicado: (2021)

Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection
por: Chan, Yi-Hao, et al.
Publicado: (2020)

Imaging adipose tissue browning using the TSPO-18kDa tracer [(18)F]FEPPA
por: Hartimath, S.V., et al.
Publicado: (2019)

Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease
por: Goggi, Julian L., et al.
Publicado: (2020)

Granzyme B PET Imaging of Immune Checkpoint Inhibitor Combinations in Colon Cancer Phenotypes
por: Goggi, J. L., et al.
Publicado: (2020)

Imaging Fibrogenesis in a Diet-Induced Model of Nonalcoholic Steatohepatitis (NASH)
por: Hartimath, S. V., et al.
Publicado: (2019)

Non-Invasive Multimodality Imaging Directly Shows TRPM4 Inhibition Ameliorates Stroke Reperfusion Injury
por: Chen, Bo, et al.
Publicado: (2018)

Imaging the Proangiogenic Effects of Cardiovascular Drugs in a Diabetic Model of Limb Ischemia
por: Goggi, J. L., et al.
Publicado: (2019)

Synthesis and Characterization in Rodent Brain of the Subtype-Selective NR2B NMDA Receptor Ligand [(11)C]Ro04-5595 as a Potential Radiotracer for Positron Emission Tomography
por: Jakobsson, Jimmy E., et al.
Publicado: (2019)

Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans
por: Zhong, Shiqi, et al.
Publicado: (2022)

Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury
por: Claser, Carla, et al.
Publicado: (2019)

Author Correction: Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury
por: Claser, Carla, et al.
Publicado: (2019)

Lectin-driven maturation of cytotoxic effector cells: the nature of effector memory
Publicado: (1977)

Early Decision: Effector and Effector Memory T Cell Differentiation in Chronic Infection
por: Opata, Michael M., et al.
Publicado: (2013)

Effectors of plant-colonizing fungi and beyond
por: Uhse, Simon, et al.
Publicado: (2018)

Sustained viremia suppression by SHIV(SF162P3CN)-recalled effector-memory CD8(+) T cells after PD1-based vaccination
por: Wong, Yik Chun, et al.
Publicado: (2021)

PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
por: Iwai, Yoshiko, et al.
Publicado: (2003)

The decay and consolidation of effector-independent motor memories
por: Bao, Shancheng, et al.
Publicado: (2022)

The Linker Histone H1.2 Is an Intermediate in the Apoptotic Response to Cytokine Deprivation in T-Effectors
por: Garg, Megha, et al.
Publicado: (2014)

Acute Malaria Induces PD1(+)CTLA4(+) Effector T Cells with Cell-Extrinsic Suppressor Function
por: Mackroth, Maria Sophia, et al.
Publicado: (2016)

Effectors and Effector Delivery in Magnaporthe oryzae
por: Zhang, Shijie, et al.
Publicado: (2014)

Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection
por: Opata, Michael M., et al.
Publicado: (2018)

Tolerogenic Vaccination Reduced Effector Memory CD4 T Cells and Induced Effector Memory Treg Cells for Type I Diabetes Treatment
por: Zhang, Jingyao, et al.
Publicado: (2013)

Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft
por: Hartimath, Siddesh V., et al.
Publicado: (2019)

Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer
por: Solomon, Viswas Raja, et al.
Publicado: (2020)

WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8(+)T Cell Memory
por: Liu, Qiao, et al.
Publicado: (2019)

Radiation Dosimetry of a Novel Adenosine A(2A) Receptor Radioligand [(11)C]Preladenant Based on PET/CT Imaging and Ex Vivo Biodistribution in Rats
por: Zhou, Xiaoyun, et al.
Publicado: (2016)

Rapid Effector Function in CD8(+) Memory T Cells
por: Lalvani, Ajit, et al.
Publicado: (1997)

Cytomegalovirus infection and progressive differentiation of effector-memory T cells
por: Pardieck, Iris N., et al.
Publicado: (2018)

MYC deficiency impairs the development of effector/memory T lymphocytes
por: Nozais, Mathis, et al.
Publicado: (2021)

PD-L1 – PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection
por: Perry, Joseph A., et al.
Publicado: (2022)

Enhanced Cross-Reactive and Polyfunctional Effector-Memory T Cell Responses by ICVAX—a Human PD1-Based Bivalent HIV-1 Gag-p41 Mosaic DNA Vaccine
por: Chen, Samantha M. Y., et al.
Publicado: (2022)

Differential contributions of central and effector memory T cells to recall responses
por: Roberts, Alan D., et al.
Publicado: (2005)

Migratory Properties of Naive, Effector, and Memory Cd8(+) T Cells
por: Weninger, Wolfgang, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_18iefisvr2gkcqkncm13e7lip4