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NCOA4 Regulates Iron Recycling and Responds to Hepcidin Activity and Lipopolysaccharide in Macrophages

Macrophages, via erythrophagocytosis, recycle iron from effete erythrocytes to newly developing red blood cells. Conversion of potentially cytotoxic levels of iron from its heme into nonheme form during iron recycling is safely accomplished via coordinated regulations of cellular iron transport and...

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Detalles Bibliográficos
Autores principales: Guggisberg, Cole A., Kim, Juyoung, Lee, Jaekwon, Chen, Xiaoli, Ryu, Moon-Suhn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598790/
https://www.ncbi.nlm.nih.gov/pubmed/36290647
http://dx.doi.org/10.3390/antiox11101926