An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation

Bacterial resistance represents a major health problem worldwide and there is an urgent need to develop first-in-class compounds directed against new therapeutic targets. We previously developed a drug-discovery platform to identify new antimicrobials able to disrupt the protein–protein interaction...

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Detalles Bibliográficos
Autores principales: Caputo, Alessia, Sartini, Sara, Levati, Elisabetta, Minato, Ilaria, Elisi, Gian Marco, Di Stasi, Adriana, Guillou, Catherine, Goekjian, Peter G., Garcia, Pierre, Gueyrard, David, Bach, Stéphane, Comte, Arnaud, Ottonello, Simone, Rivara, Silvia, Montanini, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598883/
https://www.ncbi.nlm.nih.gov/pubmed/36290107
http://dx.doi.org/10.3390/antibiotics11101449

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