Design and Synthesis of (Z)-5-(Substituted benzylidene)-3-cyclohexyl-2-thioxothiazolidin-4-one Analogues as Anti-Tyrosinase and Antioxidant Compounds: In Vitro and In Silico Insights

Many compounds containing the β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold, including cinnamamide derivatives, have been shown to inhibit tyrosinase potently in vitro and in vivo. Structural changes to cinnamamide derivatives were produced by adding a dithionate functional group to provide eigh...

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Detalles Bibliográficos
Autores principales: Ko, Jeongin, Lee, Jieun, Jung, Hee Jin, Ullah, Sultan, Jeong, Yeongmu, Hong, Sojeong, Kang, Min Kyung, Park, Yu Jung, Hwang, YeJi, Kang, Dongwan, Park, Yujin, Chun, Pusoon, Yoo, Jin-Wook, Chung, Hae Young, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598926/
https://www.ncbi.nlm.nih.gov/pubmed/36290640
http://dx.doi.org/10.3390/antiox11101918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598926/
https://www.ncbi.nlm.nih.gov/pubmed/36290640
http://dx.doi.org/10.3390/antiox11101918

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