MicroRNA-4732-3p Is Dysregulated in Breast Cancer Patients with Cardiotoxicity, and Its Therapeutic Delivery Protects the Heart from Doxorubicin-Induced Oxidative Stress in Rats

Anthracycline-induced cardiotoxicity is the most severe collateral effect of chemotherapy originated by an excess of oxidative stress in cardiomyocytes that leads to cardiac dysfunction. We assessed clinical data from patients with breast cancer receiving anthracyclines and searched for discriminati...

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Autores principales: Sánchez-Sánchez, Rafael, Reinal, Ignacio, Peiró-Molina, Esteban, Buigues, Marc, Tejedor, Sandra, Hernándiz, Amparo, Selva, Marta, Hervás, David, Cañada, Antonio J., Dorronsoro, Akaitz, Santaballa, Ana, Salvador, Carmen, Caiment, Florian, Kleinjans, Jos, Martínez-Dolz, Luis, Moscoso, Isabel, Lage, Ricardo, González-Juanatey, José R., Panadero, Joaquín, Aparicio-Puerta, Ernesto, Bernad, Antonio, Sepúlveda, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599023/
https://www.ncbi.nlm.nih.gov/pubmed/36290678
http://dx.doi.org/10.3390/antiox11101955

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