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CD44 Promotes Breast Cancer Metastasis through AKT-Mediated Downregulation of Nuclear FOXA2

The primary cause of breast cancer mortality is the metastatic invasion of cancerous stem cells (CSC). Cluster of differentiation 44 (CD44) is a well-known CSC marker in various cancers, as well as a key role player in metastasis and relapse of breast cancer. CD44 is a cell-membrane embedded protein...

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Detalles Bibliográficos
Autores principales: Vadhan, Anupama, Hou, Ming-Feng, Vijayaraghavan, Priya, Wu, Yi-Chia, Hu, Stephen Chu-Sung, Wang, Yun-Ming, Cheng, Tian-Lu, Wang, Yen-Yun, Yuan, Shyng-Shiou F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599046/
https://www.ncbi.nlm.nih.gov/pubmed/36289750
http://dx.doi.org/10.3390/biomedicines10102488