Cargando…
New Betulin Derivatives with Nitrogen Heterocyclic Moiety—Synthesis and Anticancer Activity In Vitro
As part of the search for new medicinal substances with potential application in oncology, the synthesis of new compounds combining the betulin molecule and the indole system was carried out. The structure of the ester derivatives obtained in the Steglich reaction was confirmed by spectroscopic meth...
Autores principales: | Bębenek, Ewa, Chrobak, Elwira, Rzepka, Zuzanna, Wrześniok, Dorota |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599051/ https://www.ncbi.nlm.nih.gov/pubmed/36291749 http://dx.doi.org/10.3390/biom12101540 |
Ejemplares similares
-
Synthesis and Anticancer Activity of Indole-Functionalized Derivatives of Betulin
por: Rzepka, Zuzanna, et al.
Publicado: (2022) -
Molecular Structure, In Vitro Anticancer Study and Molecular Docking of New Phosphate Derivatives of Betulin
por: Chrobak, Elwira, et al.
Publicado: (2021) -
New acetylenic derivatives of betulin and betulone,
synthesis and cytotoxic activity
por: Bębenek, Ewa, et al.
Publicado: (2016) -
Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde
por: Bębenek, Ewa, et al.
Publicado: (2019) -
Anticancer Activity of the Acetylenic Derivative of Betulin Phosphate Involves Induction of Necrotic-Like Death in Breast Cancer Cells In Vitro
por: Orchel, Arkadiusz, et al.
Publicado: (2021)