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Functional Tuning of Intrinsically Disordered Regions in Human Proteins by Composition Bias

Intrinsically disordered regions (IDRs) in protein sequences are flexible, have low structural constraints and as a result have faster rates of evolution. This lack of evolutionary conservation greatly limits the use of sequence homology for the classification and functional assessment of IDRs, as o...

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Detalles Bibliográficos
Autores principales:	Kastano, Kristina, Mier, Pablo, Dosztányi, Zsuzsanna, Promponas, Vasilis J., Andrade-Navarro, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599065/ https://www.ncbi.nlm.nih.gov/pubmed/36291695 http://dx.doi.org/10.3390/biom12101486

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