Cargando…

Pulmonary Thrombosis Promotes Tumorigenesis via Myeloid Hypoxia-Inducible Factors

Cancer patients have a greater risk of thrombosis than individuals without cancer. Conversely, thrombosis is a diagnostic predictor of cancer, but the mechanisms by which thrombosis promotes tumor propagation are incompletely understood. Our previous studies showed that hypoxia-inducible factors (HI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xiao, Prodger, Alice, Sim, Jingwei, Evans, Colin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599092/ https://www.ncbi.nlm.nih.gov/pubmed/36291563 http://dx.doi.org/10.3390/biom12101354

Ejemplares similares

Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis
por: Evans, Colin E., et al.
Publicado: (2017)

Hypoxia‐inducible factor‐1 α deletion in myeloid lineage attenuates hypoxia‐induced pulmonary hypertension
por: Kojima, Hiroshi, et al.
Publicado: (2019)

Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function
por: Walmsley, Sarah R, et al.
Publicado: (2009)

Hypoxia and HIF activation as a possible link between sepsis and thrombosis
por: Evans, Colin E.
Publicado: (2019)

Salidroside ameliorated hypoxia‐induced tumorigenesis of BxPC‐3 cells via downregulating hypoxia‐inducible factor (HIF)‐1α and LOXL2
por: Chen, Xiaoping, et al.
Publicado: (2019)

Hypoxia-induced circCCDC66 promotes the tumorigenesis of colorectal cancer via the miR-3140/autophagy pathway
por: Feng, Jin, et al.
Publicado: (2020)

Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5
por: Feng, Xing, et al.
Publicado: (2020)

Myeloid Cell Hypoxia-Inducible Factors Promote Resolution of Inflammation in Experimental Colitis
por: Lin, Nan, et al.
Publicado: (2018)

Down-regulation of LINC00472 promotes osteosarcoma tumorigenesis by reducing FOXO1 expressions via miR-300
por: Zhang, Jingwei, et al.
Publicado: (2020)

Tumorigenesis: Cell Defense Against Hypoxia?
por: Pakravan, Nafiseh
Publicado: (2013)

Myeloid Translocation Gene-16 Co-Repressor Promotes Degradation of Hypoxia-Inducible Factor 1
por: Kumar, Parveen, et al.
Publicado: (2015)

Hypoxia-induced lncRNA RBM5-AS1 promotes tumorigenesis via activating Wnt/β-catenin signaling in breast cancer
por: Li, Xinping, et al.
Publicado: (2022)

Hypoxia-Inducible Factor Signaling in Inflammatory Lung Injury and Repair
por: Evans, Colin E.
Publicado: (2022)

Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis
por: Zhou, Jingying, et al.
Publicado: (2023)

Preeclampsia, Hypoxia, Thrombosis, and Inflammation
por: Shamshirsaz, Amir A., et al.
Publicado: (2012)

Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection
por: Shepardson, Kelly M., et al.
Publicado: (2014)

Intermittent hypoxia-induced downregulation of microRNA-320b promotes lung cancer tumorigenesis by increasing CDT1 via USP37
por: Li, Weihao, et al.
Publicado: (2021)

Deletion of Vascular Endothelial Growth Factor in myeloid cells accelerates tumorigenesis
por: Stockmann, Christian, et al.
Publicado: (2008)

Hypoxia-induced myeloid derived growth factor promotes hepatocellular carcinoma progression through remodeling tumor microenvironment
por: Wang, Xu, et al.
Publicado: (2021)

Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance
por: Ikeda, Kazuhiro, et al.
Publicado: (2019)

Hypoxia-inducible transcription factor-1α promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway
por: Luo, FengMing, et al.
Publicado: (2006)

RNA demethylase ALKBH5 promotes tumorigenesis of t (8;21) acute myeloid leukemia via ITPA m6A modification
por: Li, Ran, et al.
Publicado: (2023)

A Hypoxia-Induced SCF(FBXL1) E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis
por: Zeng, Jun, et al.
Publicado: (2022)

Annexin A2 promotion of hepatocellular carcinoma tumorigenesis via the immune microenvironment
por: Qiu, Li-Wei, et al.
Publicado: (2020)

Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye
por: Gardner, Peter J., et al.
Publicado: (2017)

LMTK3 promotes tumorigenesis in bladder cancer via the ERK/MAPK pathway
por: Jiang, Tao, et al.
Publicado: (2020)

The role of hypoxia-induced long noncoding RNAs (lncRNAs) in tumorigenesis and metastasis
por: Peng, Pei-Hua, et al.
Publicado: (2021)

The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia
por: Sim, Jingwei, et al.
Publicado: (2018)

Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis
por: Chen, Hsiao-Fan, et al.
Publicado: (2016)

Editorial: Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis, and Therapeutics
por: Gomez, Christian R.
Publicado: (2016)

Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway
por: Feng, Tingting, et al.
Publicado: (2016)

Arterial Thrombosis in Patients with Acute Myeloid Leukemia: Incidence and Risk Factors
por: Mitrovic, Mirjana, et al.
Publicado: (2023)

Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamics
por: Chen, Xi, et al.
Publicado: (2019)

Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis
por: Youssif, Catrin, et al.
Publicado: (2018)

Editorial: Highlights in Thrombosis: 2021
por: Evans, Colin E.
Publicado: (2022)

Ginsenoside-Rg1 mediates a hypoxia-independent upregulation of hypoxia-inducible factor-1α to promote angiogenesis
por: Leung, Kar-Wah, et al.
Publicado: (2011)

Lack of Bcr and Abr Promotes Hypoxia-Induced Pulmonary Hypertension in Mice
por: Yu, Min, et al.
Publicado: (2012)

Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival
por: Pelletier, Joffrey, et al.
Publicado: (2012)

Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair
por: DeBerge, Matthew, et al.
Publicado: (2021)

The Myeloid Immune Signature of Enterotoxigenic Bacteroides Fragilis-Induced Murine Colon Tumorigenesis
por: Orberg, Erik Thiele, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_hlths7gj7pa0uu80rdo1gcd22i