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Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series
Behavioural Activation (BA) is associated with a substantial evidence base for treatment of acute unipolar depression, and has promise as an easily disseminable psychological intervention for bipolar depression. Using a randomised multiple baseline case series design we examined the feasibility and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599144/ https://www.ncbi.nlm.nih.gov/pubmed/36291340 http://dx.doi.org/10.3390/brainsci12101407 |
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author | Wright, Kim Mostazir, Mohammod Bailey, Ella Dunn, Barnaby D. O’Mahen, Heather Sibsey, Michaela Thomas, Zoe |
author_facet | Wright, Kim Mostazir, Mohammod Bailey, Ella Dunn, Barnaby D. O’Mahen, Heather Sibsey, Michaela Thomas, Zoe |
author_sort | Wright, Kim |
collection | PubMed |
description | Behavioural Activation (BA) is associated with a substantial evidence base for treatment of acute unipolar depression, and has promise as an easily disseminable psychological intervention for bipolar depression. Using a randomised multiple baseline case series design we examined the feasibility and acceptability of an adapted version of BA in a U.K. outpatient sample of 12 adults with acute bipolar depression. Participants were allocated at random to a 3–8 week wait period before being offered up to 20 sessions of BA. They completed outcome measures at intake, pre- and post-treatment and weekly symptom measures across the study period. Retention in therapy was high (11/12 participants completed the target minimum number of sessions), and all participants returning acceptability measures reported high levels of satisfaction with the intervention. No therapy-related serious adverse events were reported, nor were there exacerbations in manic symptoms that were judged to be a result of the intervention. The pattern of change on outcome measures is consistent with the potential for clinical benefit; six of the nine participants with a stable baseline showed clinically significant improvement on the primary outcome measure. The findings suggest adapted BA for bipolar depression is a feasible and acceptable approach that merits further investigation. |
format | Online Article Text |
id | pubmed-9599144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95991442022-10-27 Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series Wright, Kim Mostazir, Mohammod Bailey, Ella Dunn, Barnaby D. O’Mahen, Heather Sibsey, Michaela Thomas, Zoe Brain Sci Article Behavioural Activation (BA) is associated with a substantial evidence base for treatment of acute unipolar depression, and has promise as an easily disseminable psychological intervention for bipolar depression. Using a randomised multiple baseline case series design we examined the feasibility and acceptability of an adapted version of BA in a U.K. outpatient sample of 12 adults with acute bipolar depression. Participants were allocated at random to a 3–8 week wait period before being offered up to 20 sessions of BA. They completed outcome measures at intake, pre- and post-treatment and weekly symptom measures across the study period. Retention in therapy was high (11/12 participants completed the target minimum number of sessions), and all participants returning acceptability measures reported high levels of satisfaction with the intervention. No therapy-related serious adverse events were reported, nor were there exacerbations in manic symptoms that were judged to be a result of the intervention. The pattern of change on outcome measures is consistent with the potential for clinical benefit; six of the nine participants with a stable baseline showed clinically significant improvement on the primary outcome measure. The findings suggest adapted BA for bipolar depression is a feasible and acceptable approach that merits further investigation. MDPI 2022-10-19 /pmc/articles/PMC9599144/ /pubmed/36291340 http://dx.doi.org/10.3390/brainsci12101407 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wright, Kim Mostazir, Mohammod Bailey, Ella Dunn, Barnaby D. O’Mahen, Heather Sibsey, Michaela Thomas, Zoe Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series |
title | Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series |
title_full | Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series |
title_fullStr | Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series |
title_full_unstemmed | Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series |
title_short | Adapted Behavioural Activation for Bipolar Depression: A Randomised Multiple Baseline Case Series |
title_sort | adapted behavioural activation for bipolar depression: a randomised multiple baseline case series |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599144/ https://www.ncbi.nlm.nih.gov/pubmed/36291340 http://dx.doi.org/10.3390/brainsci12101407 |
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