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Receptor Transporter Protein 4 (RTP4) in the Hypothalamus Is Involved in the Development of Antinociceptive Tolerance to Morphine

Receptor transporter protein 4 (RTP4), one of the receptor chaperone proteins, contributes to the maturation and membrane trafficking of opioid receptor heteromers consisting of mu (MOPr) and delta (DOPr) opioid receptors (MOPr-DOPr). Although MOPr-DOPr is known to mediate the development of morphin...

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Detalles Bibliográficos
Autores principales: Fujita, Wakako, Uchida, Hitoshi, Kawanishi, Masashi, Kuroiwa, Yusuke, Abe, Manabu, Sakimura, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599210/
https://www.ncbi.nlm.nih.gov/pubmed/36291680
http://dx.doi.org/10.3390/biom12101471