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Investigating p62 Concentrations in Cerebrospinal Fluid of Patients with Dementia: A Potential Autophagy Biomarker In Vivo?

Several studies have revealed defects in autophagy in neurodegenerative disorders including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). SQSTM1/p62 plays a key role in the autophagic machinery and may serve as a marker for autophagic flux in vivo. We investigated the role of p62 in ne...

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Detalles Bibliográficos
Autores principales:	Rubino, Elisa, Boschi, Silvia, Roveta, Fausto, Marcinnò, Andrea, Cermelli, Aurora, Borghese, Cristina, Vigliani, Maria Claudia, Rainero, Innocenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599226/ https://www.ncbi.nlm.nih.gov/pubmed/36291347 http://dx.doi.org/10.3390/brainsci12101414

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