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Targeting Mitochondrial Function with Chemoptogenetics

Mitochondria are ATP-generating organelles in eukaryotic cells that produce reactive oxygen species (ROS) during oxidative phosphorylation (OXPHOS). Mitochondrial DNA (mtDNA) is packaged within nucleoids and, due to its close proximity to ROS production, endures oxidative base damage. This damage ca...

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Detalles Bibliográficos
Autores principales:	Romesberg, Amy, Van Houten, Bennett
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599259/ https://www.ncbi.nlm.nih.gov/pubmed/36289721 http://dx.doi.org/10.3390/biomedicines10102459

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