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Crystal Structure of the Human Copper Chaperone ATOX1 Bound to Zinc Ion

The bioavailability of copper (Cu) in human cells may depend on a complex interplay with zinc (Zn) ions. We investigated the ability of the Zn ion to target the human Cu-chaperone Atox1, a small cytosolic protein capable of anchoring Cu(I), by a conserved surface-exposed Cys-X-X-Cys (CXXC) motif, an...

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Detalles Bibliográficos
Autores principales:	Mangini, Vincenzo, Belviso, Benny Danilo, Nardella, Maria Incoronata, Natile, Giovanni, Arnesano, Fabio, Caliandro, Rocco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599288/ https://www.ncbi.nlm.nih.gov/pubmed/36291703 http://dx.doi.org/10.3390/biom12101494

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