Interleukin-26–DNA complexes promote inflammation and dermal-epidermal separation in a modified human cryosection model of bullous pemphigoid

Bullous pemphigoid (BP) is an autoimmune disease characterized by autoantibody-mediated activation of immune cells and subepidermal blister formation. Excess amounts of extracellular DNA are produced in BP, however, it remains unclear how extracellular DNA contributes to BP pathogenesis. Here we sho...

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Detalles Bibliográficos
Autores principales: Mizuno, Yuka, Shibata, Sayaka, Ito, Yukiko, Taira, Haruka, Sugimoto, Eiki, Awaji, Kentaro, Sato, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599390/
https://www.ncbi.nlm.nih.gov/pubmed/36311716
http://dx.doi.org/10.3389/fimmu.2022.1013382

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