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Discovery of MAO-B Inhibitor with Machine Learning, Topomer CoMFA, Molecular Docking and Multi-Spectroscopy Approaches

Alzheimer’s disease (AD) is the most common type of dementia and is a serious disruption to normal life. Monoamine oxidase-B (MAO-B) is an important target for the treatment of AD. In this study, machine learning approaches were applied to investigate the identification model of MAO-B inhibitors. Th...

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Detalles Bibliográficos
Autores principales:	Zheng, Linfeng, Qin, Xiangyang, Wang, Jiao, Zhang, Mengying, An, Quanlin, Xu, Jinzhi, Qu, Xiaosheng, Cao, Xin, Niu, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599443/ https://www.ncbi.nlm.nih.gov/pubmed/36291679 http://dx.doi.org/10.3390/biom12101470

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