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Defining the HIV Capsid Binding Site of Nucleoporin 153

The interaction between the HIV-1 capsid and human nucleoporin 153 (NUP153) is vital for delivering the HIV-1 preintegration complex into the nucleus via the nuclear pore complex. The interaction with the capsid requires a phenylalanine/glycine-containing motif in the C-terminus of NUP153 (NUP153C)....

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Detalles Bibliográficos
Autores principales: Li, Shunji, Patel, Jagdish Suresh, Yang, Jordan, Crabtree, Angela Marie, Rubenstein, Brenda Marilyn, Lund-Andersen, Peik Karl, Ytreberg, Frederick Marty, Rowley, Paul Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599535/
https://www.ncbi.nlm.nih.gov/pubmed/36040047
http://dx.doi.org/10.1128/msphere.00310-22