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Dissecting Naturally Arising Amino Acid Substitutions at Position L452 of SARS-CoV-2 Spike

Mutations at spike protein L452 are recurrently observed in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC), including omicron lineages. It remains elusive how amino acid substitutions at L452 are selected in VOC. Here, we characterized all 19 possible mutation...

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Detalles Bibliográficos
Autores principales:	Tan, Toong Seng, Toyoda, Mako, Ode, Hirotaka, Barabona, Godfrey, Hamana, Hiroshi, Kitamatsu, Mizuki, Kishi, Hiroyuki, Motozono, Chihiro, Iwatani, Yasumasa, Ueno, Takamasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599599/ https://www.ncbi.nlm.nih.gov/pubmed/36214577 http://dx.doi.org/10.1128/jvi.01162-22

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