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A Microfluidic In Vitro Three-Dimensional Dynamic Model of the Blood–Brain Barrier to Study the Transmigration of Immune Cells

To study the biodistribution of new chemical and biological entities, an in vitro model of the blood–brain barrier (BBB) may become an essential tool during early phases of drug discovery. Here, we present a proof-of-concept of an in-house designed three-dimensional BBB biochip designed by us. This...

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Detalles Bibliográficos
Autores principales: Meena, Megha, Vandormael, Robin, De Laere, Maxime, Pintelon, Isabel, Berneman, Zwi, Watts, Regan, Cools, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599663/
https://www.ncbi.nlm.nih.gov/pubmed/36291227
http://dx.doi.org/10.3390/brainsci12101293