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A Microfluidic In Vitro Three-Dimensional Dynamic Model of the Blood–Brain Barrier to Study the Transmigration of Immune Cells
To study the biodistribution of new chemical and biological entities, an in vitro model of the blood–brain barrier (BBB) may become an essential tool during early phases of drug discovery. Here, we present a proof-of-concept of an in-house designed three-dimensional BBB biochip designed by us. This...
Autores principales: | Meena, Megha, Vandormael, Robin, De Laere, Maxime, Pintelon, Isabel, Berneman, Zwi, Watts, Regan, Cools, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599663/ https://www.ncbi.nlm.nih.gov/pubmed/36291227 http://dx.doi.org/10.3390/brainsci12101293 |
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