OGG1 Inhibition Reduces Acinar Cell Injury in a Mouse Model of Acute Pancreatitis

Acute pancreatitis (AP) is a potentially life-threatening gastrointestinal disease with a complex pathology including oxidative stress. Oxidative stress triggers oxidative DNA lesions such as formation of 7,8-dihydro-8-oxo-2′-oxoguanine (8-oxoG) and also causes DNA strand breaks. DNA breaks can acti...

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Detalles Bibliográficos
Autores principales: Hajnády, Zoltán, Nagy-Pénzes, Máté, Demény, Máté A., Kovács, Katalin, El-Hamoly, Tarek, Maléth, József, Hegyi, Péter, Polgár, Zsuzsanna, Hegedűs, Csaba, Virág, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599718/
https://www.ncbi.nlm.nih.gov/pubmed/36289805
http://dx.doi.org/10.3390/biomedicines10102543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599718/
https://www.ncbi.nlm.nih.gov/pubmed/36289805
http://dx.doi.org/10.3390/biomedicines10102543

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