Elevated Extracellular HSP72 and Blunted Heat Shock Response in Severe COVID-19 Patients

Aims: We hypothesized that critically ill patients with SARS-CoV-2 infection and insulin resistance would present a reduced Heat Shock Response (HSR), which is a pathway involved in proteostasis and anti-inflammation, subsequently leading to worse outcomes and higher inflammation. In this work we ai...

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Detalles Bibliográficos
Autores principales: Borges Russo, Mariana Kras, Kowalewski, Lucas Stahlhöfer, da Natividade, Gabriella Richter, de Lemos Muller, Carlos Henrique, Schroeder, Helena Trevisan, Bock, Patrícia Martins, Ayres, Layane Ramos, Cardoso, Bernardo Urbano, Zanotto, Caroline, Schein, Julia Tsao, Rech, Tatiana Helena, Crispim, Daisy, Canani, Luis Henrique, Friedman, Rogério, Leitão, Cristiane Bauermann, Gerchman, Fernando, Krause, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599720/
https://www.ncbi.nlm.nih.gov/pubmed/36291584
http://dx.doi.org/10.3390/biom12101374

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