The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal

Prdm1 mutant mice are one of the rare mutant strains that do not develop whisker hair follicles while still displaying a pelage. Here, we show that Prdm1 is expressed at the earliest stage of whisker development in clusters of mesenchymal cells before placode formation. Its conditional knockout in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Manti, Pierluigi G., Darbellay, Fabrice, Leleu, Marion, Coughlan, Aisling Y., Moret, Bernard, Cuennet, Julien, Droux, Frederic, Stoudmann, Magali, Mancini, Gian-Filippo, Hautier, Agnès, Sordet-Dessimoz, Jessica, Vincent, Stephane D., Testa, Giuseppe, Cossu, Giulio, Barrandon, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599752/
https://www.ncbi.nlm.nih.gov/pubmed/36289911
http://dx.doi.org/10.3390/biomedicines10102647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599752/
https://www.ncbi.nlm.nih.gov/pubmed/36289911
http://dx.doi.org/10.3390/biomedicines10102647

Ejemplares similares