The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal

Prdm1 mutant mice are one of the rare mutant strains that do not develop whisker hair follicles while still displaying a pelage. Here, we show that Prdm1 is expressed at the earliest stage of whisker development in clusters of mesenchymal cells before placode formation. Its conditional knockout in t...

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Detalles Bibliográficos
Autores principales: Manti, Pierluigi G., Darbellay, Fabrice, Leleu, Marion, Coughlan, Aisling Y., Moret, Bernard, Cuennet, Julien, Droux, Frederic, Stoudmann, Magali, Mancini, Gian-Filippo, Hautier, Agnès, Sordet-Dessimoz, Jessica, Vincent, Stephane D., Testa, Giuseppe, Cossu, Giulio, Barrandon, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599752/
https://www.ncbi.nlm.nih.gov/pubmed/36289911
http://dx.doi.org/10.3390/biomedicines10102647

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