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Pancreatic Cancer Research beyond DNA Mutations
Pancreatic ductal adenocarcinoma (PDAC) is caused by genetic mutations in four genes: KRAS proto-oncogene and GTPase (KRAS), tumor protein P53 (TP53), cyclin-dependent kinase inhibitor 2A (CDKN2A), and mothers against decapentaplegic homolog 4 (SMAD4), also called the big 4. The changes in tumors ar...
Autores principales: | Sato, Hiromichi, Sasaki, Kazuki, Hara, Tomoaki, Tsuji, Yoshiko, Arao, Yasuko, Otsuka, Chihiro, Hamano, Yumiko, Ogita, Mirei, Kobayashi, Shogo, di Luccio, Eric, Hirotsu, Takaaki, Doki, Yuichiro, Eguchi, Hidetoshi, Satoh, Taroh, Uchida, Shizuka, Ishii, Hideshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599774/ https://www.ncbi.nlm.nih.gov/pubmed/36291712 http://dx.doi.org/10.3390/biom12101503 |
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