Cargando…

Selecting Multitarget Peptides for Alzheimer’s Disease

Alzheimer’s disease (AD) is a multifactorial disease with a complex pathogenesis. Developing multitarget drugs could be a powerful strategy to impact the progressive loss of cognitive functions in this disease. The purpose of this study is to select a multitarget lead peptide candidate among a serie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kasus-Jacobi, Anne, Washburn, Jennifer L., Laurence, Riley B., Pereira, H. Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599826/ https://www.ncbi.nlm.nih.gov/pubmed/36291595 http://dx.doi.org/10.3390/biom12101386

Ejemplares similares

Antimicrobial Peptides Derived from the Immune Defense Protein CAP37 Inhibit TLR4 Activation by S100A9
por: Kasus-Jacobi, Anne, et al.
Publicado: (2020)

The role of neutrophil granule proteins in neuroinflammation and Alzheimer’s disease
por: Stock, Amanda J., et al.
Publicado: (2018)

Bioactive Antimicrobial Peptides as Therapeutics for Corneal Wounds and Infections
por: Griffith, Gina L., et al.
Publicado: (2017)

The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer’s disease
por: Brock, Amanda J., et al.
Publicado: (2015)

Effect of Cationic Antimicrobial Protein CAP37 on Cytokine Profile during Corneal Wound Healing
por: Kasus-Jacobi, Anne, et al.
Publicado: (2017)

Multitarget therapeutic strategies for Alzheimer’s disease
por: Ibrahim, Mostafa M., et al.
Publicado: (2019)

Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease
por: Marotta, Giambattista, et al.
Publicado: (2020)

Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer’s and Other Neurodegenerative Diseases
por: Cornec, Anne-Sophie, et al.
Publicado: (2017)

Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease
por: Grishchenko, Maria V., et al.
Publicado: (2022)

The Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis
por: Stock, Amanda J., et al.
Publicado: (2016)

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer’s disease
por: Hafez, Donia E., et al.
Publicado: (2023)

A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer’s Disease
por: Bolognino, Isabella, et al.
Publicado: (2019)

Multitarget Therapeutic Strategies for Alzheimer's Disease: Review on Emerging Target Combinations
por: Maramai, Samuele, et al.
Publicado: (2020)

Marine Natural Products, Multitarget Therapy and Repurposed Agents in Alzheimer’s Disease
por: Martins, Márcia, et al.
Publicado: (2020)

Licochalcone A: A Potential Multitarget Drug for Alzheimer’s Disease Treatment
por: Olloquequi, Jordi, et al.
Publicado: (2023)

A Definition of “Multitargeticity”: Identifying Potential Multitarget and Selective Ligands Through a Vector Analysis
por: Sánchez-Tejeda, Juan Francisco, et al.
Publicado: (2020)

Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment
por: Dakhlaoui, Imen, et al.
Publicado: (2023)

Towards Multitarget Testing in Molecular Microbiology
por: Steensels, Deborah, et al.
Publicado: (2013)

Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer’s disease
por: Wu, Wen-Yu, et al.
Publicado: (2017)

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease
por: Chaves, Sílvia, et al.
Publicado: (2020)

From Single Target to Multitarget/Network Therapeutics in Alzheimer’s Therapy
por: Zheng, Hailin, et al.
Publicado: (2014)

In Silico and In Vitro Studies of Benzothiazole-Isothioureas Derivatives as a Multitarget Compound for Alzheimer’s Disease
por: Rosales Hernández, Martha Cecilia, et al.
Publicado: (2022)

Novel Donepezil–Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer’s Disease
por: Queda, Fausto, et al.
Publicado: (2021)

Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease
por: Makhaeva, Galina F., et al.
Publicado: (2023)

Multitarget Therapeutics for Neurodegenerative Diseases
por: Gabr, Moustafa T., et al.
Publicado: (2020)

Effects of Linkers and Substitutions on Multitarget Directed Ligands for Alzheimer’s Diseases: Emerging Paradigms and Strategies
por: Pravin, Narayanaperumal, et al.
Publicado: (2022)

Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer’s Disease
por: Prati, Federica, et al.
Publicado: (2016)

Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer’s Disease
por: Campora, Marta, et al.
Publicado: (2021)

Exploring the Multitarget Activity of Wedelolactone against Alzheimer’s Disease: Insights from In Silico Study
por: Du, Dang Xuan, et al.
Publicado: (2023)

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer’s Disease
por: Rajeshwari, Rajeshwari, et al.
Publicado: (2019)

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis
por: Sampietro, Anna, et al.
Publicado: (2022)

Multitarget Activities of Kleeb Bua Daeng, a Thai Traditional Herbal Formula, Against Alzheimer’s Disease
por: Chheng, Chantha, et al.
Publicado: (2020)

Study on the Multitarget Synergistic Effects of Kai-Xin-San against Alzheimer's Disease Based on Systems Biology
por: Guo, Sirui, et al.
Publicado: (2019)

Multigram Synthesis and in Vivo Efficacy Studies of a Novel Multitarget Anti-Alzheimer’s Compound
por: Sola, Irene, et al.
Publicado: (2015)

Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer’s Disease
por: Mirza, Fatima Javed, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking-Based Strategy to Investigate the Multitarget Mechanisms of Shenqi Yizhi Granule on Alzheimer's Disease
por: Wang, Linshuang, et al.
Publicado: (2022)

Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider
por: Finol-Urdaneta, Rocio K., et al.
Publicado: (2022)

Multitarget Drug Design, Molecular Docking and PLIF Studies of Novel Tacrine−Coumarin Hybrids for the Treatment of Alzheimer’s Disease
por: Fereidoonnezhad, Masood, et al.
Publicado: (2018)

From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein‐Templated Synthesis
por: Nozal, Vanesa, et al.
Publicado: (2021)

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases
por: Li, Kai, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rd085ivjjl1iilfn7rm6897ptf