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Porphyromonas gingivalis Outer Membrane Vesicles Stimulate Gingival Epithelial Cells to Induce Pro-Inflammatory Cytokines via the MAPK and STING Pathways

Porphyromonas gingivalis (Pg) is a keystone pathogen associated with chronic periodontitis and produces outer membrane vesicles (OMVs) that contain lipopolysaccharide (LPS), gingipains, and pathogen-derived DNA and RNA. Pg-OMVs are involved in the pathogenesis of periodontitis. Pg-OMV-activated path...

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Detalles Bibliográficos
Autores principales: Uemura, Yuta, Hiroshima, Yuka, Tada, Ayano, Murakami, Keiji, Yoshida, Kaya, Inagaki, Yuji, Kuwahara, Tomomi, Murakami, Akikazu, Fujii, Hideki, Yumoto, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599832/
https://www.ncbi.nlm.nih.gov/pubmed/36289904
http://dx.doi.org/10.3390/biomedicines10102643