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Porphyromonas gingivalis Outer Membrane Vesicles Stimulate Gingival Epithelial Cells to Induce Pro-Inflammatory Cytokines via the MAPK and STING Pathways
Porphyromonas gingivalis (Pg) is a keystone pathogen associated with chronic periodontitis and produces outer membrane vesicles (OMVs) that contain lipopolysaccharide (LPS), gingipains, and pathogen-derived DNA and RNA. Pg-OMVs are involved in the pathogenesis of periodontitis. Pg-OMV-activated path...
Autores principales: | Uemura, Yuta, Hiroshima, Yuka, Tada, Ayano, Murakami, Keiji, Yoshida, Kaya, Inagaki, Yuji, Kuwahara, Tomomi, Murakami, Akikazu, Fujii, Hideki, Yumoto, Hiromichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599832/ https://www.ncbi.nlm.nih.gov/pubmed/36289904 http://dx.doi.org/10.3390/biomedicines10102643 |
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