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A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study
Background: The cost of heart failure hospitalizations in the US alone is over USD 10 billion per year. Over 4 million Americans are hospitalized every year due to heart failure (HF), with a median length of stay of 4 days and an in-hospital mortality rate that exceeds 5%. Hospitalizations of patien...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599847/ https://www.ncbi.nlm.nih.gov/pubmed/36290968 http://dx.doi.org/10.3390/bios12100833 |
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author | Merdler, Ilan Hochstadt, Aviram Ghantous, Eihab Lupu, Lior Borohovitz, Ariel Zahler, David Taieb, Philippe Sadeh, Ben Zalevsky, Zeev Garcia-Monreal, Javier Shergei, Michael Shatsky, Maxim Beck, Yoav Polani, Sagi Arbel, Yaron |
author_facet | Merdler, Ilan Hochstadt, Aviram Ghantous, Eihab Lupu, Lior Borohovitz, Ariel Zahler, David Taieb, Philippe Sadeh, Ben Zalevsky, Zeev Garcia-Monreal, Javier Shergei, Michael Shatsky, Maxim Beck, Yoav Polani, Sagi Arbel, Yaron |
author_sort | Merdler, Ilan |
collection | PubMed |
description | Background: The cost of heart failure hospitalizations in the US alone is over USD 10 billion per year. Over 4 million Americans are hospitalized every year due to heart failure (HF), with a median length of stay of 4 days and an in-hospital mortality rate that exceeds 5%. Hospitalizations of patients with HF can be prevented by early detection of lung congestion. Our study assessed a new contact-free optical medical device used for the early detection of lung congestion. Methods: The Gili system is an FDA-cleared device used for measuring chest motion vibration data. Lung congestion in the study was assessed clinically and verified via two cardiologists. An algorithm was developed using machine learning techniques, and cross-validation of the findings was performed to estimate the accuracy of the algorithm. Results: A total of 227 patients were recruited (101 cases vs. 126 controls). The sensitivity and specificity for the device in our study were 0.91 (95% CI: 0.86–0.93) and 0.91 (95% CI: 0.87–0.94), respectively. In all instances, the observed estimates of PPVs and NPVs were at least 0.82 and 0.90, respectively. The accuracy of the algorithm was not affected by different covariates (including respiratory or valvular conditions). Conclusions: This study demonstrates the efficacy of a contact-free optical device for detecting lung congestion. Further validation of the study results across a larger and precise scale is warranted. |
format | Online Article Text |
id | pubmed-9599847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95998472022-10-27 A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study Merdler, Ilan Hochstadt, Aviram Ghantous, Eihab Lupu, Lior Borohovitz, Ariel Zahler, David Taieb, Philippe Sadeh, Ben Zalevsky, Zeev Garcia-Monreal, Javier Shergei, Michael Shatsky, Maxim Beck, Yoav Polani, Sagi Arbel, Yaron Biosensors (Basel) Article Background: The cost of heart failure hospitalizations in the US alone is over USD 10 billion per year. Over 4 million Americans are hospitalized every year due to heart failure (HF), with a median length of stay of 4 days and an in-hospital mortality rate that exceeds 5%. Hospitalizations of patients with HF can be prevented by early detection of lung congestion. Our study assessed a new contact-free optical medical device used for the early detection of lung congestion. Methods: The Gili system is an FDA-cleared device used for measuring chest motion vibration data. Lung congestion in the study was assessed clinically and verified via two cardiologists. An algorithm was developed using machine learning techniques, and cross-validation of the findings was performed to estimate the accuracy of the algorithm. Results: A total of 227 patients were recruited (101 cases vs. 126 controls). The sensitivity and specificity for the device in our study were 0.91 (95% CI: 0.86–0.93) and 0.91 (95% CI: 0.87–0.94), respectively. In all instances, the observed estimates of PPVs and NPVs were at least 0.82 and 0.90, respectively. The accuracy of the algorithm was not affected by different covariates (including respiratory or valvular conditions). Conclusions: This study demonstrates the efficacy of a contact-free optical device for detecting lung congestion. Further validation of the study results across a larger and precise scale is warranted. MDPI 2022-10-06 /pmc/articles/PMC9599847/ /pubmed/36290968 http://dx.doi.org/10.3390/bios12100833 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Merdler, Ilan Hochstadt, Aviram Ghantous, Eihab Lupu, Lior Borohovitz, Ariel Zahler, David Taieb, Philippe Sadeh, Ben Zalevsky, Zeev Garcia-Monreal, Javier Shergei, Michael Shatsky, Maxim Beck, Yoav Polani, Sagi Arbel, Yaron A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study |
title | A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study |
title_full | A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study |
title_fullStr | A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study |
title_full_unstemmed | A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study |
title_short | A Contact-Free Optical Device for the Detection of Pulmonary Congestion—A Pilot Study |
title_sort | contact-free optical device for the detection of pulmonary congestion—a pilot study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599847/ https://www.ncbi.nlm.nih.gov/pubmed/36290968 http://dx.doi.org/10.3390/bios12100833 |
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