Expression of Amyloid Precursor Protein, Caveolin-1, Alpha-, Beta-, and Gamma-Secretases in Penumbra Cells after Photothrombotic Stroke and Evaluation of Neuroprotective Effect of Secretase and Caveolin-1 Inhibitors

Our studies reveal changes in the expression of the main participants in the processing of amyloid precursor protein (APP) in neurons and astrocytes after photothrombotic stroke (PTS). Here we show the increase in the level of N- and C-terminal fragments of APP in the cytoplasm of ischemic penumbra...

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Detalles Bibliográficos
Autores principales: Sharifulina, Svetlana, Khaitin, Andrey, Guzenko, Valeria, Kalyuzhnaya, Yuliya, Dzreyan, Valentina, Logvinov, Alexandr, Dobaeva, Natalia, Li, Yan, Chen, Lei, He, Bin, Demyanenko, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599860/
https://www.ncbi.nlm.nih.gov/pubmed/36289917
http://dx.doi.org/10.3390/biomedicines10102655

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