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Inhibition of Malate Dehydrogenase-2 Protects Renal Tubular Epithelial Cells from Anoxia-Reoxygenation-Induced Death or Senescence

Ischemia-reperfusion injury is the leading cause of acute kidney injury. Reactive oxygen species (ROS) production causes cell death or senescence. In cultures of primary human renal tubular epithelial cells (RPTECs) subjected to anoxia-reoxygenation, inhibition of the Krebs cycle at the level of mal...

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Detalles Bibliográficos
Autores principales:	Eleftheriadis, Theodoros, Pissas, Georgios, Golfinopoulos, Spyridon, Efthymiadi, Maria, Liakopoulos, Vassilios, Stefanidis, Ioannis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599925/ https://www.ncbi.nlm.nih.gov/pubmed/36291624 http://dx.doi.org/10.3390/biom12101415

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