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Upregulation of Succinate Dehydrogenase (SDHA) Contributes to Enhanced Bioenergetics of Ovarian Cancer Cells and Higher Sensitivity to Anti-Metabolic Agent Shikonin
SIMPLE SUMMARY: In recent years, targeting tumor specific metabolism has gained an interest as a promising therapeutic strategy. We discovered that the overexpression of mitochondrial enzyme succinate dehydrogenase (SDHA) is highly prevalent in ovarian carcinoma patients and contributes to elevated...
Autores principales: | Wang, Lin, Cybula, Magdalena, Rostworowska, Maria, Wang, Luyao, Mucha, Patryk, Bulicz, Magdalena, Bieniasz, Magdalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599980/ https://www.ncbi.nlm.nih.gov/pubmed/36291881 http://dx.doi.org/10.3390/cancers14205097 |
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