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Upregulation of Succinate Dehydrogenase (SDHA) Contributes to Enhanced Bioenergetics of Ovarian Cancer Cells and Higher Sensitivity to Anti-Metabolic Agent Shikonin

SIMPLE SUMMARY: In recent years, targeting tumor specific metabolism has gained an interest as a promising therapeutic strategy. We discovered that the overexpression of mitochondrial enzyme succinate dehydrogenase (SDHA) is highly prevalent in ovarian carcinoma patients and contributes to elevated...

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Detalles Bibliográficos
Autores principales:	Wang, Lin, Cybula, Magdalena, Rostworowska, Maria, Wang, Luyao, Mucha, Patryk, Bulicz, Magdalena, Bieniasz, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599980/ https://www.ncbi.nlm.nih.gov/pubmed/36291881 http://dx.doi.org/10.3390/cancers14205097

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