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Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells

Reprogramming of energy metabolism is regarded as one of the hallmarks of cancer; in particular, oncogenic RAS has been shown to be a critical regulator of cancer metabolism. Recently, asparagine metabolism has been heavily investigated as a novel target for cancer treatment. For example, Knott et a...

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Detalles Bibliográficos
Autores principales: Nishikawa, Gen, Kawada, Kenji, Hanada, Keita, Maekawa, Hisatsugu, Itatani, Yoshiro, Miyoshi, Hiroyuki, Taketo, Makoto Mark, Obama, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600002/
https://www.ncbi.nlm.nih.gov/pubmed/36291140
http://dx.doi.org/10.3390/cells11203273