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Chromosomal Instability, Selection and Competition: Factors That Shape the Level of Karyotype Intra-Tumor Heterogeneity

SIMPLE SUMMARY: Each cancer consists of billions of cells. These cells are far from identical; hence, the population of cells that constitute a tumor is heterogeneous. A salient property that varies between cells in a tumor is their karyotype, the number and configuration of the chromosomes. The lev...

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Detalles Bibliográficos
Autores principales: van den Bosch, Tom, Derks, Sarah, Miedema, Daniël M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600040/
https://www.ncbi.nlm.nih.gov/pubmed/36291770
http://dx.doi.org/10.3390/cancers14204986

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