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A Rapid, Simple, Trace, Cost-Effective, and High-Throughput Stable Isotope-Dilution Liquid Chromatography–Tandem Mass Spectrometry Method for Serum Methylmalonic Acid Quantification and Its Clinical Applications

HIGHLIGHTS: What are the main findings? An established method for trace, simple, rapid, cheap, sensitive, accurate, robust, and high-throughput for methylmalonic acid quantification. Good chromatographic separation of MMA and its intrinsic isomer and good signals of MMA were achieved using a simple...

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Detalles Bibliográficos
Autores principales: Jin, Lizi, Liu, Zhenni, Zhou, Weiyan, Zeng, Jie, Wu, Minhang, Zhang, Yu, Zhang, Tianjiao, He, Falin, Zhang, Chuanbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600096/
https://www.ncbi.nlm.nih.gov/pubmed/36291963
http://dx.doi.org/10.3390/diagnostics12102273