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Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion

Pannexin1 (Panx1) is expressed in both neurons and glia where it forms ATP-permeable channels that are activated under pathological conditions such as epilepsy, migraine, inflammation, and ischemia. Membrane lipid composition affects proper distribution and function of receptors and ion channels, an...

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Detalles Bibliográficos
Autores principales: Cibelli, Antonio, Scemes, Eliana, Spray, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600160/
https://www.ncbi.nlm.nih.gov/pubmed/36291086
http://dx.doi.org/10.3390/cells11203219

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