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MITF Is Regulated by Redox Signals Controlled by the Selenoprotein Thioredoxin Reductase 1

SIMPLE SUMMARY: Melanomas and the melanocytes from which they arise are subject to the damaging effects of reactive oxygen species (ROS) from exogenous and endogenous sources. Many attempts have been made to counteract these effects with antioxidant drugs and natural products. Here, we demonstrate t...

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Detalles Bibliográficos
Autores principales: Kline, Chelsey D., Anderson, Madeleine, Bassett, John W., Kent, Gail, Berryman, Rachel, Honeggar, Matthew, Ito, Shosuke, Wakamatsu, Kazumasa, Indra, Arup K., Moos, Philip J., Leachman, Sancy A., Cassidy, Pamela B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600194/
https://www.ncbi.nlm.nih.gov/pubmed/36291795
http://dx.doi.org/10.3390/cancers14205011