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Detection and Classification of Knee Osteoarthritis
Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600223/ https://www.ncbi.nlm.nih.gov/pubmed/36292051 http://dx.doi.org/10.3390/diagnostics12102362 |
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author | Cueva, Joseph Humberto Castillo, Darwin Espinós-Morató, Héctor Durán, David Díaz, Patricia Lakshminarayanan, Vasudevan |
author_facet | Cueva, Joseph Humberto Castillo, Darwin Espinós-Morató, Héctor Durán, David Díaz, Patricia Lakshminarayanan, Vasudevan |
author_sort | Cueva, Joseph Humberto |
collection | PubMed |
description | Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-automatic CADx model based on Deep Siamese convolutional neural networks and a fine-tuned ResNet-34 to simultaneously detect OA lesions in the two knees according to the KL scale. The training was done using a public dataset, whereas the validations were performed with a private dataset. Some problems of the imbalanced dataset were solved using transfer learning. The model results average of the multi-class accuracy is 61%, presenting better performance results for classifying classes KL-0, KL-3, and KL-4 than KL-1 and KL-2. The classification results were compared and validated using the classification of experienced radiologists. |
format | Online Article Text |
id | pubmed-9600223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96002232022-10-27 Detection and Classification of Knee Osteoarthritis Cueva, Joseph Humberto Castillo, Darwin Espinós-Morató, Héctor Durán, David Díaz, Patricia Lakshminarayanan, Vasudevan Diagnostics (Basel) Article Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-automatic CADx model based on Deep Siamese convolutional neural networks and a fine-tuned ResNet-34 to simultaneously detect OA lesions in the two knees according to the KL scale. The training was done using a public dataset, whereas the validations were performed with a private dataset. Some problems of the imbalanced dataset were solved using transfer learning. The model results average of the multi-class accuracy is 61%, presenting better performance results for classifying classes KL-0, KL-3, and KL-4 than KL-1 and KL-2. The classification results were compared and validated using the classification of experienced radiologists. MDPI 2022-09-29 /pmc/articles/PMC9600223/ /pubmed/36292051 http://dx.doi.org/10.3390/diagnostics12102362 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cueva, Joseph Humberto Castillo, Darwin Espinós-Morató, Héctor Durán, David Díaz, Patricia Lakshminarayanan, Vasudevan Detection and Classification of Knee Osteoarthritis |
title | Detection and Classification of Knee Osteoarthritis |
title_full | Detection and Classification of Knee Osteoarthritis |
title_fullStr | Detection and Classification of Knee Osteoarthritis |
title_full_unstemmed | Detection and Classification of Knee Osteoarthritis |
title_short | Detection and Classification of Knee Osteoarthritis |
title_sort | detection and classification of knee osteoarthritis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600223/ https://www.ncbi.nlm.nih.gov/pubmed/36292051 http://dx.doi.org/10.3390/diagnostics12102362 |
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