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Detection and Classification of Knee Osteoarthritis

Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-a...

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Autores principales: Cueva, Joseph Humberto, Castillo, Darwin, Espinós-Morató, Héctor, Durán, David, Díaz, Patricia, Lakshminarayanan, Vasudevan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600223/
https://www.ncbi.nlm.nih.gov/pubmed/36292051
http://dx.doi.org/10.3390/diagnostics12102362
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author Cueva, Joseph Humberto
Castillo, Darwin
Espinós-Morató, Héctor
Durán, David
Díaz, Patricia
Lakshminarayanan, Vasudevan
author_facet Cueva, Joseph Humberto
Castillo, Darwin
Espinós-Morató, Héctor
Durán, David
Díaz, Patricia
Lakshminarayanan, Vasudevan
author_sort Cueva, Joseph Humberto
collection PubMed
description Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-automatic CADx model based on Deep Siamese convolutional neural networks and a fine-tuned ResNet-34 to simultaneously detect OA lesions in the two knees according to the KL scale. The training was done using a public dataset, whereas the validations were performed with a private dataset. Some problems of the imbalanced dataset were solved using transfer learning. The model results average of the multi-class accuracy is 61%, presenting better performance results for classifying classes KL-0, KL-3, and KL-4 than KL-1 and KL-2. The classification results were compared and validated using the classification of experienced radiologists.
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spelling pubmed-96002232022-10-27 Detection and Classification of Knee Osteoarthritis Cueva, Joseph Humberto Castillo, Darwin Espinós-Morató, Héctor Durán, David Díaz, Patricia Lakshminarayanan, Vasudevan Diagnostics (Basel) Article Osteoarthritis (OA) affects nearly 240 million people worldwide. Knee OA is the most common type of arthritis, especially in older adults. Physicians measure the severity of knee OA according to the Kellgren and Lawrence (KL) scale through visual inspection of X-ray or MR images. We propose a semi-automatic CADx model based on Deep Siamese convolutional neural networks and a fine-tuned ResNet-34 to simultaneously detect OA lesions in the two knees according to the KL scale. The training was done using a public dataset, whereas the validations were performed with a private dataset. Some problems of the imbalanced dataset were solved using transfer learning. The model results average of the multi-class accuracy is 61%, presenting better performance results for classifying classes KL-0, KL-3, and KL-4 than KL-1 and KL-2. The classification results were compared and validated using the classification of experienced radiologists. MDPI 2022-09-29 /pmc/articles/PMC9600223/ /pubmed/36292051 http://dx.doi.org/10.3390/diagnostics12102362 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cueva, Joseph Humberto
Castillo, Darwin
Espinós-Morató, Héctor
Durán, David
Díaz, Patricia
Lakshminarayanan, Vasudevan
Detection and Classification of Knee Osteoarthritis
title Detection and Classification of Knee Osteoarthritis
title_full Detection and Classification of Knee Osteoarthritis
title_fullStr Detection and Classification of Knee Osteoarthritis
title_full_unstemmed Detection and Classification of Knee Osteoarthritis
title_short Detection and Classification of Knee Osteoarthritis
title_sort detection and classification of knee osteoarthritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600223/
https://www.ncbi.nlm.nih.gov/pubmed/36292051
http://dx.doi.org/10.3390/diagnostics12102362
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