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Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism

Introduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications. Methods: An observational study was conducted on 32 consecu...

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Autores principales: Klasnja, Slobodan, Manojlovic, Andrea, Popadic, Viseslav, Ivankovic, Tatjana, Ninkovic, Nebojsa, Rajovic, Nina, Popovic, Maja, Nikolic, Novica, Brajkovic, Milica, Radojevic, Aleksandra, Lasica, Ratko, Rajsic, Sasa, Todorovic, Zoran, Brankovic, Marija, Radonjic, Tijana, Memon, Lidija, Mrda, Davor, Milic, Natasa, Zdravkovic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600333/
https://www.ncbi.nlm.nih.gov/pubmed/36292069
http://dx.doi.org/10.3390/diagnostics12102380
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author Klasnja, Slobodan
Manojlovic, Andrea
Popadic, Viseslav
Ivankovic, Tatjana
Ninkovic, Nebojsa
Rajovic, Nina
Popovic, Maja
Nikolic, Novica
Brajkovic, Milica
Radojevic, Aleksandra
Lasica, Ratko
Rajsic, Sasa
Todorovic, Zoran
Brankovic, Marija
Radonjic, Tijana
Memon, Lidija
Mrda, Davor
Milic, Natasa
Zdravkovic, Marija
author_facet Klasnja, Slobodan
Manojlovic, Andrea
Popadic, Viseslav
Ivankovic, Tatjana
Ninkovic, Nebojsa
Rajovic, Nina
Popovic, Maja
Nikolic, Novica
Brajkovic, Milica
Radojevic, Aleksandra
Lasica, Ratko
Rajsic, Sasa
Todorovic, Zoran
Brankovic, Marija
Radonjic, Tijana
Memon, Lidija
Mrda, Davor
Milic, Natasa
Zdravkovic, Marija
author_sort Klasnja, Slobodan
collection PubMed
description Introduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications. Methods: An observational study was conducted on 32 consecutive patients with confirmed pulmonary embolism and COVID-19 infection treated in the Intensive Care Unit of the University Hospital Medical Center “Bežanijska kosa”, Belgrade, Serbia, between April 2021 and March 2022. Predictors of the need for oxygen support were determined, while point-of-care echocardiographic parameters and various anamnestic, laboratory, and clinically significant parameters were correlated with the Pulmonary Embolism Severity Index (PESI) score. Results: More than two-thirds of patients in our study had PE symptoms present at hospital admission (68.8%). The majority of patients had segmental pulmonary embolism (48.4%), with high to very high PESI score values in 31.3% of patients. Pneumonia was present in 68.8% of the study population. The PESI score was negatively correlated with diastolic blood pressure and SaO2 at the time of PE diagnosis, LV ejection fraction, and PVAT. A positive correlation was found between the PESI score, maximum CRP, and D-dimer at the time of PTE diagnosis. A larger right ventricular diameter was associated with a greater need for oxygen support. Conclusion: Point-of-care echocardiography is a valuable tool for the risk assessment of COVID-19 patients with pulmonary embolism. Right ventricular size stood out as a significant marker of disease severity.
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spelling pubmed-96003332022-10-27 Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism Klasnja, Slobodan Manojlovic, Andrea Popadic, Viseslav Ivankovic, Tatjana Ninkovic, Nebojsa Rajovic, Nina Popovic, Maja Nikolic, Novica Brajkovic, Milica Radojevic, Aleksandra Lasica, Ratko Rajsic, Sasa Todorovic, Zoran Brankovic, Marija Radonjic, Tijana Memon, Lidija Mrda, Davor Milic, Natasa Zdravkovic, Marija Diagnostics (Basel) Article Introduction: Thrombotic complications, such as pulmonary embolism, are common in COVID-19 patients. Point-of-care ultrasound is a highly recommended tool for orientation in critically ill patients with suspected or confirmed complications. Methods: An observational study was conducted on 32 consecutive patients with confirmed pulmonary embolism and COVID-19 infection treated in the Intensive Care Unit of the University Hospital Medical Center “Bežanijska kosa”, Belgrade, Serbia, between April 2021 and March 2022. Predictors of the need for oxygen support were determined, while point-of-care echocardiographic parameters and various anamnestic, laboratory, and clinically significant parameters were correlated with the Pulmonary Embolism Severity Index (PESI) score. Results: More than two-thirds of patients in our study had PE symptoms present at hospital admission (68.8%). The majority of patients had segmental pulmonary embolism (48.4%), with high to very high PESI score values in 31.3% of patients. Pneumonia was present in 68.8% of the study population. The PESI score was negatively correlated with diastolic blood pressure and SaO2 at the time of PE diagnosis, LV ejection fraction, and PVAT. A positive correlation was found between the PESI score, maximum CRP, and D-dimer at the time of PTE diagnosis. A larger right ventricular diameter was associated with a greater need for oxygen support. Conclusion: Point-of-care echocardiography is a valuable tool for the risk assessment of COVID-19 patients with pulmonary embolism. Right ventricular size stood out as a significant marker of disease severity. MDPI 2022-09-30 /pmc/articles/PMC9600333/ /pubmed/36292069 http://dx.doi.org/10.3390/diagnostics12102380 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Klasnja, Slobodan
Manojlovic, Andrea
Popadic, Viseslav
Ivankovic, Tatjana
Ninkovic, Nebojsa
Rajovic, Nina
Popovic, Maja
Nikolic, Novica
Brajkovic, Milica
Radojevic, Aleksandra
Lasica, Ratko
Rajsic, Sasa
Todorovic, Zoran
Brankovic, Marija
Radonjic, Tijana
Memon, Lidija
Mrda, Davor
Milic, Natasa
Zdravkovic, Marija
Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
title Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
title_full Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
title_fullStr Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
title_full_unstemmed Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
title_short Point-of-Care Echocardiographic Characteristics of COVID-19 Patients with Pulmonary Embolism
title_sort point-of-care echocardiographic characteristics of covid-19 patients with pulmonary embolism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600333/
https://www.ncbi.nlm.nih.gov/pubmed/36292069
http://dx.doi.org/10.3390/diagnostics12102380
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