Synthesis and In Silico Study of Some New bis-[1,3,4]thiadiazolimines and bis-Thiazolimines as Potential Inhibitors for SARS-CoV-2 Main Protease

A novel series of bis-[1,3,4]thiadiazolimines, and bis-thiazolimines, with alkyl linker, were synthesized through general routes from cyclization of 1,1′-(hexane-1,6-diyl)bis(3-phenylthiourea) and hydrazonoyl halides or α-haloketones, respectively. Docking studies were applied to test the binding af...

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Detalles Bibliográficos
Autores principales: Gomha, Sobhi M., Riyadh, Sayed M., Abdellattif, Magda H., Abolibda, Tariq Z., Abdel-aziz, Hassan M., Nayl, AbdElAziz. A., Elgohary, Alaa M., Elfiky, Abdo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600414/
https://www.ncbi.nlm.nih.gov/pubmed/36286026
http://dx.doi.org/10.3390/cimb44100311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600414/
https://www.ncbi.nlm.nih.gov/pubmed/36286026
http://dx.doi.org/10.3390/cimb44100311

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