DNA Methyltransferase Regulates Nitric Oxide Homeostasis and Virulence in a Chronically Adapted Pseudomonas aeruginosa Strain

Opportunistic pathogens such as Pseudomonas aeruginosa adapt their genomes rapidly during chronic infections. Understanding their epigenetic regulation may provide biomarkers for diagnosis and reveal novel regulatory mechanisms. We performed single-molecule real-time sequencing (SMRT-seq) to charact...

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Detalles Bibliográficos
Autores principales: Han, Shuhong, Liu, Jihong, Li, Mianhuan, Zhang, Yizhou, Duan, Xiangke, Zhang, Yingdan, Chen, Hao, Cai, Zhao, Yang, Liang, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600465/
https://www.ncbi.nlm.nih.gov/pubmed/36106744
http://dx.doi.org/10.1128/msystems.00434-22

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