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Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status

Malnutrition is a public health problem in developing countries, affecting the child population, which favors the appearance of infections such as oral candidiasis. In Mexico, information on the presence of oral colonization by Candida spp. in asymptomatic children is scarce. The present study aimed...

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Autores principales: Pinto-Almazán, Rodolfo, Frías-De-León, María Guadalupe, Fuentes-Venado, Claudia Erika, Arenas, Roberto, González-Gutiérrez, Leopoldo, Chávez-Gutiérrez, Edwin, Torres-Paez, Oscar Uriel, Martínez-Herrera, Erick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600554/
https://www.ncbi.nlm.nih.gov/pubmed/36291446
http://dx.doi.org/10.3390/children9101510
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author Pinto-Almazán, Rodolfo
Frías-De-León, María Guadalupe
Fuentes-Venado, Claudia Erika
Arenas, Roberto
González-Gutiérrez, Leopoldo
Chávez-Gutiérrez, Edwin
Torres-Paez, Oscar Uriel
Martínez-Herrera, Erick
author_facet Pinto-Almazán, Rodolfo
Frías-De-León, María Guadalupe
Fuentes-Venado, Claudia Erika
Arenas, Roberto
González-Gutiérrez, Leopoldo
Chávez-Gutiérrez, Edwin
Torres-Paez, Oscar Uriel
Martínez-Herrera, Erick
author_sort Pinto-Almazán, Rodolfo
collection PubMed
description Malnutrition is a public health problem in developing countries, affecting the child population, which favors the appearance of infections such as oral candidiasis. In Mexico, information on the presence of oral colonization by Candida spp. in asymptomatic children is scarce. The present study aimed to determine the presence of Candida spp. in the oral cavity of asymptomatic preschool Mexican children and its association with their nutritional status. A sample of oral mucosa was obtained using a sterile swab and then inoculated in Sabouraud dextrose agar with antibiotics, and the yeast growth was phenotypically identified. The anthropometric profile of children was performed based on the guidelines of the International Society for the Advancement of Kinanthropometry. In addition, eating habits were investigated. The possible associations between the variables were determined through the chi-square test (IC95%, p < 0.05) (GraphPad Prism 8.0). Among the 743 assessed children (403 boys and 340 girls), the average age was 4.6 years, and the average nutritional status was normal (53.7%), followed by undernutrition (28.4%), overweight (12.4%) and obesity (5.5%). In 52 children, Candida was isolated, and the identified species were C. albicans (87.8%), C. glabrata (11.5%), C. krusei (5.8%) and C. parapsilosis (1.9%). The frequency of colonization was greater in males of six years (69.23%). There was no significant association between the colonization by Candida spp. and the nutritional status; however, a relation was observed with a high intake of simple carbohydrates.
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spelling pubmed-96005542022-10-27 Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status Pinto-Almazán, Rodolfo Frías-De-León, María Guadalupe Fuentes-Venado, Claudia Erika Arenas, Roberto González-Gutiérrez, Leopoldo Chávez-Gutiérrez, Edwin Torres-Paez, Oscar Uriel Martínez-Herrera, Erick Children (Basel) Article Malnutrition is a public health problem in developing countries, affecting the child population, which favors the appearance of infections such as oral candidiasis. In Mexico, information on the presence of oral colonization by Candida spp. in asymptomatic children is scarce. The present study aimed to determine the presence of Candida spp. in the oral cavity of asymptomatic preschool Mexican children and its association with their nutritional status. A sample of oral mucosa was obtained using a sterile swab and then inoculated in Sabouraud dextrose agar with antibiotics, and the yeast growth was phenotypically identified. The anthropometric profile of children was performed based on the guidelines of the International Society for the Advancement of Kinanthropometry. In addition, eating habits were investigated. The possible associations between the variables were determined through the chi-square test (IC95%, p < 0.05) (GraphPad Prism 8.0). Among the 743 assessed children (403 boys and 340 girls), the average age was 4.6 years, and the average nutritional status was normal (53.7%), followed by undernutrition (28.4%), overweight (12.4%) and obesity (5.5%). In 52 children, Candida was isolated, and the identified species were C. albicans (87.8%), C. glabrata (11.5%), C. krusei (5.8%) and C. parapsilosis (1.9%). The frequency of colonization was greater in males of six years (69.23%). There was no significant association between the colonization by Candida spp. and the nutritional status; however, a relation was observed with a high intake of simple carbohydrates. MDPI 2022-10-03 /pmc/articles/PMC9600554/ /pubmed/36291446 http://dx.doi.org/10.3390/children9101510 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pinto-Almazán, Rodolfo
Frías-De-León, María Guadalupe
Fuentes-Venado, Claudia Erika
Arenas, Roberto
González-Gutiérrez, Leopoldo
Chávez-Gutiérrez, Edwin
Torres-Paez, Oscar Uriel
Martínez-Herrera, Erick
Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status
title Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status
title_full Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status
title_fullStr Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status
title_full_unstemmed Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status
title_short Frequency of Candida spp. in the Oral Cavity of Asymptomatic Preschool Mexican Children and Its Association with Nutritional Status
title_sort frequency of candida spp. in the oral cavity of asymptomatic preschool mexican children and its association with nutritional status
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600554/
https://www.ncbi.nlm.nih.gov/pubmed/36291446
http://dx.doi.org/10.3390/children9101510
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