Dysfunctional Glymphatic System with Disrupted Aquaporin 4 Expression Pattern on Astrocytes Causes Bacterial Product Accumulation in the CSF during Pneumococcal Meningitis

Pneumococcal meningitis, inflammation of the meninges due to an infection of the Central Nervous System caused by Streptococcus pneumoniae (the pneumococcus), is the most common form of community-acquired bacterial meningitis globally. Aquaporin 4 (AQP4) water channels on astrocytic end feet regulat...

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Detalles Bibliográficos
Autores principales: Generoso, Jaqueline S., Thorsdottir, Sigrun, Collodel, Allan, Dominguini, Diogo, Santo, Roberta R. E., Petronilho, Fabricia, Barichello, Tatiana, Iovino, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600563/
https://www.ncbi.nlm.nih.gov/pubmed/36036510
http://dx.doi.org/10.1128/mbio.01886-22

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