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CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir

HIV infects long-lived CD4 memory T cells, establishing a latent viral reservoir that necessitates lifelong antiretroviral therapy (ART). How this reservoir is formed so quickly after infection remains unclear. We now show the innate inflammatory response to HIV infection results in CCL2 chemokine r...

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Detalles Bibliográficos
Autores principales: Packard, Thomas A., Schwarzer, Roland, Herzig, Eytan, Rao, Deepashri, Luo, Xiaoyu, Egedal, Johanne H., Hsiao, Feng, Widera, Marek, Hultquist, Judd F., Grimmett, Zachary W., Messer, Ronald J., Krogan, Nevan J., Deeks, Steven G., Roan, Nadia R., Dittmer, Ulf, Hasenkrug, Kim J., Greene, Warner C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600577/
https://www.ncbi.nlm.nih.gov/pubmed/36073812
http://dx.doi.org/10.1128/mbio.01891-22