Cargando…

CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir

HIV infects long-lived CD4 memory T cells, establishing a latent viral reservoir that necessitates lifelong antiretroviral therapy (ART). How this reservoir is formed so quickly after infection remains unclear. We now show the innate inflammatory response to HIV infection results in CCL2 chemokine r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Packard, Thomas A., Schwarzer, Roland, Herzig, Eytan, Rao, Deepashri, Luo, Xiaoyu, Egedal, Johanne H., Hsiao, Feng, Widera, Marek, Hultquist, Judd F., Grimmett, Zachary W., Messer, Ronald J., Krogan, Nevan J., Deeks, Steven G., Roan, Nadia R., Dittmer, Ulf, Hasenkrug, Kim J., Greene, Warner C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600577/ https://www.ncbi.nlm.nih.gov/pubmed/36073812 http://dx.doi.org/10.1128/mbio.01891-22

Ejemplares similares

Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir
por: Sutter, Kathrin, et al.
Publicado: (2019)

Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C–C Chemokine Receptor Type 5 Co-receptor Expression and Cellular Activation Status
por: Pedersen, Jesper G., et al.
Publicado: (2021)

Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection
por: Egedal, Johanne H., et al.
Publicado: (2021)

Anti-CCL2: building a reservoir or opening the floodgates to metastasis?
por: Hitchcock, Jessica R, et al.
Publicado: (2015)

Differential network biology
por: Ideker, Trey, et al.
Publicado: (2012)

Mapping genetic interactions in cancer: a road to rational combination therapies
por: Tutuncuoglu, Beril, et al.
Publicado: (2019)

Signals and systems
por: Krogan, Nevan J, et al.
Publicado: (2006)

The next frontier of systems biology: higher-order and interspecies interactions
por: Fischbach, Michael A, et al.
Publicado: (2010)

Creating collaboration by breaking down scientific barriers
por: Fabius, Jacqueline M., et al.
Publicado: (2021)

Lessons learned for pandemic preparedness: A collaborative network is imperative
por: Fabius, Jacqueline M., et al.
Publicado: (2023)

Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses
por: Dornfeld, Dominik, et al.
Publicado: (2018)

SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses
por: Dornfeld, Dominik, et al.
Publicado: (2018)

Regulatory T cells suppress virus-specific antibody responses to Friend retrovirus infection
por: Moore, Tyler C., et al.
Publicado: (2018)

Towards accurate imputation of quantitative genetic interactions
por: Ulitsky, Igor, et al.
Publicado: (2009)

CC chemokines CCL2, CCL3, CCL4 and CCL5 are elevated in osteoporosis patients
por: Farangis, Fatehi, et al.
Publicado: (2017)

Mass spectrometry‐based protein–protein interaction networks for the study of human diseases
por: Richards, Alicia L, et al.
Publicado: (2021)

Revisiting CCL-type chemokines in breast cancer and its milieu: prominent targetable chemokines, CCL8 and CCL21
por: Unver, Nese
Publicado: (2021)

Biomarker reveals HIV's hidden reservoir
por: Cockerham, Leslie R, et al.
Publicado: (2014)

Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2
por: Halford, William P., et al.
Publicado: (2015)

Functional Maps of Protein Complexes from Quantitative Genetic Interaction Data
por: Bandyopadhyay, Sourav, et al.
Publicado: (2008)

Cullin E3 Ligases and Their Rewiring by Viral Factors
por: Mahon, Cathal, et al.
Publicado: (2014)

Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response Mutants
por: Sánchez, Arancha, et al.
Publicado: (2015)

Target Discovery for Host-Directed Antiviral Therapies: Application of Proteomics Approaches
por: Cakir, Merve, et al.
Publicado: (2021)

Current proteomics methods applicable to dissecting the DNA damage response
por: Muralidharan, Monita, et al.
Publicado: (2023)

All or Nothing: Protein Complexes Flip Essentiality between Distantly Related Eukaryotes
por: Ryan, Colm J., et al.
Publicado: (2013)

Regulatory T cells in retroviral infections
por: Hasenkrug, Kim J., et al.
Publicado: (2018)

Lactate Dehydrogenase-Elevating Virus Induces Systemic Lymphocyte Activation via TLR7-Dependent IFNα Responses by Plasmacytoid Dendritic Cells
por: Ammann, Christoph G., et al.
Publicado: (2009)

Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir
por: Neidleman, Jason, et al.
Publicado: (2020)

Application of CRISPR-Cas9 Gene Editing for HIV Host Factor Discovery and Validation
por: Cisneros, William J., et al.
Publicado: (2022)

Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic Cells
por: Amati, Anca-Laura, et al.
Publicado: (2017)

A strategy for extracting and analyzing large-scale quantitative epistatic interaction data
por: Collins, Sean R, et al.
Publicado: (2006)

Adventures in time and space: Splicing efficiency and RNA polymerase II elongation rate
por: Moehle, Erica A, et al.
Publicado: (2014)

Evolution and functional cross‐talk of protein post‐translational modifications
por: Beltrao, Pedro, et al.
Publicado: (2013)

Conditional Genetic Interactions of RTT107, SLX4, and HRQ1 Reveal Dynamic Networks upon DNA Damage in S. cerevisiae
por: Leung, Grace P., et al.
Publicado: (2014)

Clinical and biological consequences of respiratory syncytial virus genetic diversity
por: Rios Guzman, Estefany, et al.
Publicado: (2022)

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors
por: Binning, Jennifer M., et al.
Publicado: (2018)

mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1
por: Du, Yushen, et al.
Publicado: (2020)

The Virus–Host Interactome: Knowing the Players to Understand the Game
por: Schneider, Monika, et al.
Publicado: (2016)

Ragweed-allergic subjects have decreased serum levels of chemokines CCL2, CCL3, CCL4 and CCL5 out of the pollen season
por: Kostova, Zhivka, et al.
Publicado: (2016)

Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells
por: Moore, Tyler C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vsjvd479fk6bjc23hqfoqkf082