Implications of Concurrent IDH1 and IDH2 Mutations on Survival in Glioma—A Case Report and Systematic Review

Both IDH1 (isocitrate dehydrogenase 1) and IDH2 (isocitrate dehydrogenase 2) mutations play a vital role in the development of gliomas through disruption of normal cellular metabolic processes. Here we describe a case of a patient with an IDH-mutant astrocytoma, in which both IDH1 and IDH2 mutations...

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Detalles Bibliográficos
Autores principales: Yuile, Alexander, Satgunaseelan, Laveniya, Wei, Joe, Kastelan, Marina, Back, Michael F., Lee, Maggie, Wei, Heng, Buckland, Michael E., Lee, Adrian, Wheeler, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600580/
https://www.ncbi.nlm.nih.gov/pubmed/36286062
http://dx.doi.org/10.3390/cimb44100348

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