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Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes
Background: An important component of asthma care is understanding potential causes of high asthma admissions (HAADs) or readmissions (HARDs) with potential of risk mitigation. Crucial to this research is accurately distinguishing these events from background seasonal changes and time trends. To dat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600648/ https://www.ncbi.nlm.nih.gov/pubmed/36292134 http://dx.doi.org/10.3390/diagnostics12102445 |
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author | Batra, Mehak Erbas, Bircan Vicendese, Don |
author_facet | Batra, Mehak Erbas, Bircan Vicendese, Don |
author_sort | Batra, Mehak |
collection | PubMed |
description | Background: An important component of asthma care is understanding potential causes of high asthma admissions (HAADs) or readmissions (HARDs) with potential of risk mitigation. Crucial to this research is accurately distinguishing these events from background seasonal changes and time trends. To date, classification methods have been based on ad hoc and untested definitions which may hamper understanding causes of HAADs and HARDs due to misclassification. The aim of this article is to introduce an easily applied robust statistical approach, with high classification accuracy in other settings—the Seasonal Hybrid Extreme Studentized Deviate (S-H-ESD) method. Methods: We demonstrate S-H-ESD on a time series between 1996 and 2009 of all daily paediatric asthma hospital admissions in Victoria, Australia. Results: S-H-ESD clearly identified HAADs and HARDs without applying ad hoc classification definitions, while appropriately accounting for seasonality and time trend. Importantly, it was done with statistical testing, providing evidence in support of their identification. Conclusion: S-H-ESD is useful and statistically appropriate for accurate classification of HAADs and HARDS. It obviates ad hoc approaches and presents as a means of systemizing their accurate classification and detection. This will strengthen synthesis and efficacy of research toward understanding causes of HAADs and HARDs for their risk mitigation. |
format | Online Article Text |
id | pubmed-9600648 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96006482022-10-27 Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes Batra, Mehak Erbas, Bircan Vicendese, Don Diagnostics (Basel) Article Background: An important component of asthma care is understanding potential causes of high asthma admissions (HAADs) or readmissions (HARDs) with potential of risk mitigation. Crucial to this research is accurately distinguishing these events from background seasonal changes and time trends. To date, classification methods have been based on ad hoc and untested definitions which may hamper understanding causes of HAADs and HARDs due to misclassification. The aim of this article is to introduce an easily applied robust statistical approach, with high classification accuracy in other settings—the Seasonal Hybrid Extreme Studentized Deviate (S-H-ESD) method. Methods: We demonstrate S-H-ESD on a time series between 1996 and 2009 of all daily paediatric asthma hospital admissions in Victoria, Australia. Results: S-H-ESD clearly identified HAADs and HARDs without applying ad hoc classification definitions, while appropriately accounting for seasonality and time trend. Importantly, it was done with statistical testing, providing evidence in support of their identification. Conclusion: S-H-ESD is useful and statistically appropriate for accurate classification of HAADs and HARDS. It obviates ad hoc approaches and presents as a means of systemizing their accurate classification and detection. This will strengthen synthesis and efficacy of research toward understanding causes of HAADs and HARDs for their risk mitigation. MDPI 2022-10-10 /pmc/articles/PMC9600648/ /pubmed/36292134 http://dx.doi.org/10.3390/diagnostics12102445 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Batra, Mehak Erbas, Bircan Vicendese, Don Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes |
title | Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes |
title_full | Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes |
title_fullStr | Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes |
title_full_unstemmed | Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes |
title_short | Asthma Hospital Admission and Readmission Spikes, Advancing Accurate Classification to Advance Understanding of Causes |
title_sort | asthma hospital admission and readmission spikes, advancing accurate classification to advance understanding of causes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600648/ https://www.ncbi.nlm.nih.gov/pubmed/36292134 http://dx.doi.org/10.3390/diagnostics12102445 |
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