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Plakoglobin and High-Mobility Group Box 1 Mediate Intestinal Epithelial Cell Apoptosis Induced by Clostridioides difficile TcdB
Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated intestinal disease, resulting in severe diarrhea and fatal pseudomembranous colitis. TcdB, one of the essential virulence factors secreted by this bacterium, induces host cell apoptosis through a poorly understood...
Autores principales: | Li, Yingxue, Xu, Wei, Ren, Yutian, Cheung, Hung-Chi, Huang, Panpan, Kaur, Guneet, Kuo, Chih-Jung, McDonough, Sean P., Fubini, Susan L., Lipkin, Stephen M., Deng, Xin, Chang, Yung-Fu, Huang, Linfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600731/ https://www.ncbi.nlm.nih.gov/pubmed/36043787 http://dx.doi.org/10.1128/mbio.01849-22 |
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