Cargando…

PARP1′s Involvement in RNA Polymerase II Elongation: Pausing and Releasing Regulation through the Integrator and Super Elongation Complex

RNA polymerase elongation along the gene body is tightly regulated to ensure proper transcription and alternative splicing events. Understanding the mechanism and factors critical in regulating the rate of RNA polymerase II elongation and processivity is clearly important. Recently we showed that PA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matveeva, Elena A., Dhahri, Hejer, Fondufe-Mittendorf, Yvonne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9600911/ https://www.ncbi.nlm.nih.gov/pubmed/36291070 http://dx.doi.org/10.3390/cells11203202

Ejemplares similares

Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing
por: Matveeva, Elena A., et al.
Publicado: (2019)

PARP1 is a versatile factor in the regulation of mRNA stability and decay
por: Matveeva, Elena A., et al.
Publicado: (2019)

Elongation rate of RNA polymerase II affects pausing patterns across 3′ UTRs
por: Khitun, Alexandra, et al.
Publicado: (2023)

Involvement of PARP1 in the regulation of alternative splicing
por: Matveeva, Elena, et al.
Publicado: (2016)

Widespread transcriptional pausing and elongation control at enhancers
por: Henriques, Telmo, et al.
Publicado: (2018)

ERK-mediated NELF-A phosphorylation promotes transcription elongation of immediate-early genes by releasing promoter-proximal pausing of RNA polymerase II
por: Ohe, Seina, et al.
Publicado: (2022)

The multifaceted role of PARP1 in RNA biogenesis
por: Eleazer, Rebekah, et al.
Publicado: (2020)

Structural transitions in the transcription elongation complexes of bacterial RNA polymerase during σ-dependent pausing
por: Zhilina, Ekaterina, et al.
Publicado: (2012)

Elongation Factor P Interactions with the Ribosome Are Independent of Pausing
por: Tollerson, Rodney, et al.
Publicado: (2017)

Basic mechanisms and kinetics of pause-interspersed transcript elongation
por: Qian, Jin, et al.
Publicado: (2020)

Rate of transcription elongation and sequence-specific pausing by RNA polymerase I directly influence rRNA processing
por: Huffines, Abigail K., et al.
Publicado: (2022)

TRIM28 regulates RNA polymerase II promoter proximal pausing and pause release
por: Bunch, Heeyoun, et al.
Publicado: (2014)

Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches
por: Castells-Garcia, Alvaro, et al.
Publicado: (2021)

Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex
por: Gopalan, Sneha, et al.
Publicado: (2018)

Control of Transcriptional Elongation by RNA Polymerase II: A Retrospective
por: Brannan, Kris, et al.
Publicado: (2012)

RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing
por: de la Mata, Manuel, et al.
Publicado: (2011)

Structure–function studies of the RNA polymerase II elongation complex
por: Brueckner, Florian, et al.
Publicado: (2009)

In vitro analysis of RNA polymerase II elongation complex dynamics
por: Joo, Yoo Jin, et al.
Publicado: (2019)

Elongation factor-specific capture of RNA polymerase II complexes
por: Gregersen, Lea H., et al.
Publicado: (2022)

DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation
por: Close, Pierre, et al.
Publicado: (2012)

Genome-wide dynamics of Pol II elongation and its interplay with promoter proximal pausing, chromatin, and exons
por: Jonkers, Iris, et al.
Publicado: (2014)

P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development
por: Dahlberg, Olle, et al.
Publicado: (2015)

Building a super elongation complex for HIV
por: Hill, Christopher P, et al.
Publicado: (2013)

ELL facilitates RNA polymerase II pause site entry and release
por: Byun, Jung S., et al.
Publicado: (2012)

NDF is a transcription factor that stimulates elongation by RNA polymerase II
por: Fei, Jia, et al.
Publicado: (2022)

Pausing for thought: Disrupting the early transcription elongation checkpoint leads to developmental defects and tumourigenesis
por: Jennings, Barbara H
Publicado: (2013)

Robust regulation of transcription pausing in Escherichia coli by the ubiquitous elongation factor NusG
por: Yakhnin, Alexander V., et al.
Publicado: (2023)

Correction: P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development
Publicado: (2015)

TFIIH is an elongation factor of RNA polymerase I
por: Assfalg, Robin, et al.
Publicado: (2012)

In-gel fluorescence detection by DNA polymerase elongation
por: Moss, Alden C., et al.
Publicado: (2020)

Colorimetry-Based Phosphate Measurement for Polymerase Elongation
por: Yang, Han, et al.
Publicado: (2023)

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes
por: Stadelmayer, Bernd, et al.
Publicado: (2014)

Enhancing HIV-1 latency reversal through regulating the elongating RNA Pol II pause-release by a small-molecule disruptor of PAF1C
por: Soliman, Shimaa H. A., et al.
Publicado: (2023)

Uniform Distribution of Elongating RNA Polymerase II Complexes in Transcribed Gene Locus
por: Peil, Kadri, et al.
Publicado: (2011)

The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing
por: Brody, Yehuda, et al.
Publicado: (2011)

Stability, Flexibility, and Dynamic Interactions of Colliding RNA Polymerase II Elongation Complexes
por: Saeki, Hideaki, et al.
Publicado: (2009)

Adventures in time and space: Splicing efficiency and RNA polymerase II elongation rate
por: Moehle, Erica A, et al.
Publicado: (2014)

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
por: Larochelle, Stéphane, et al.
Publicado: (2012)

Molecular Basis for 5-Carboxycytosine Recognition by RNA Polymerase II Elongation Complex
por: Wang, Lanfeng, et al.
Publicado: (2015)

Statistical inference of the rate of RNA polymerase II elongation by total RNA sequencing
por: Kawamura, Yumi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hpnrqmmig0752nq9l5d27ecnl1